Nancy Karlton Crews, 79, of Lake City, Florida, passed away on December 16, 2025. She was born on August 12, 1946, in Louisville, Kentucky, to James H. Johnston, Sr. and Martha Hines.  Nancy worked for many years as a dental hygienist and later retired from the Columbia County Health Department. She was a proud member of the Blue Gray Army and the Lake City Seminole Club, enjoyed attending Bobby Bowden Day, and was an avid Florida State Seminoles fan. One of her greatest joys was spending time on the Suwannee River with her husband, Frankie, and riding the John Deere Gator to visit friends. She was also a longstanding member of Gateway Baptist Church. She is preceded in death by her first husband, George Karlton; her brother, Jim Johnston; and her sister, Barbara Minchin.

She is survived by her husband, Frankie Crews, of Lake City; her sons Matthew Karlton (Lyndi) and Chip Karlton (Denise); and her stepsons Brian Crews (Karena) and Brett Crews (Celena), all of Lake City.  She is also survived by her grandchildren: Riley Karlton, Keston Karlton, Hayes Karlton, Turner Crews (Jenna), Weston Crews, Meredyth Crews, Houston Crews, Brody Crews, and Mayken Crews; and her great‑grandchildren, Paislynn Crews and Callan Crews.

A funeral service will be conducted at Gateway‑Forest Lawn Funeral Home Memorial Chapel on Friday, December 19, 2025, at 11:00 a.m. Interment will follow at Forest Lawn Memorial Gardens.  In lieu of flowers, donations can be made to Haven Hospice or Gateway Baptist Church.